A crucial set of U.S. economic releases is coming up this week, and each one has the potential to shift sentiment across both traditional markets and the crypto sector. After weeks of elevated volatility, investors are watching inflation indicators, labor data, and holiday-affected trading schedules to gauge whether the current macro pressure will ease, or intensify.
Crypto markets tend to react sharply to macroeconomic shifts, especially when expectations around interest rates change. With several high-impact reports arriving in a compressed window, traders should prepare for sudden swings in Bitcoin, Ethereum, and altcoins as liquidity thins during the Thanksgiving period.
PPI Inflation Data – Tuesday, November 25
The week begins with Producer Price Index (PPI) data, a key measure of wholesale inflation. Rising PPI often signals future upward pressure on consumer prices, which can push the Federal Reserve toward a more defensive stance. If the report surprises to the upside, markets may brace for tighter monetary expectations, a scenario that typically weighs on crypto.
A softer reading, however, could fuel expectations of rate cuts in early 2026, potentially boosting risk assets.
Initial Jobless Claims – Wednesday, November 26
Labor market data remains one of the most influential macro indicators for both equities and digital assets. Initial Jobless Claims will reveal whether layoffs are increasing, which could indicate slowing economic momentum.
Higher-than-expected jobless claims tend to support the narrative of easing inflation and a more dovish Fed, a short-term bullish catalyst for crypto. Conversely, a strong labor reading could pressure markets by suggesting that rate relief is still far off.
PCE Inflation Report – Wednesday, November 26
The most important data of the week arrives mid-day Wednesday: the Personal Consumption Expenditures (PCE) Index, the Fed’s preferred inflation gauge. PCE carries far more weight than CPI or PPI because it captures consumer spending behaviors and adjusts for substitution.
A hotter-than-expected PCE could trigger immediate volatility across Bitcoin and major altcoins, especially with reduced liquidity heading into Thanksgiving. A cooler reading, however, may ignite a relief rally as markets re-price the likelihood of earlier rate cuts.
Thanksgiving Market Closures – November 27 & 28
The U.S. stock market will be closed on Thursday and will operate on an early schedule Friday, creating a two-day period of thin liquidity across global risk assets.
Low-volume trading environments often amplify volatility in crypto, especially if unexpected macro headlines emerge while U.S. markets are offline. Traders should be prepared for exaggerated price moves during these windows.
Final Thoughts
This week presents a cluster of macroeconomic catalysts that could significantly influence crypto price direction. With PPI, jobless claims, and the pivotal PCE report landing just before a major market holiday, volatility is almost guaranteed. Whether this leads to a bullish breakout or renewed downside will depend heavily on how inflation trends line up against the Federal Reserve’s expectations.
Crypto investors should stay alert, manage risk carefully, and be prepared for fast-moving market conditions as the data rolls in.

